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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

SARM1 activation triggers axon degeneration locally via NAD+ destruction
SARM1 activation triggers axon degeneration locally via NAD+ destruction

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

NAD+ in Brain Aging and Neurodegenerative Disorders
NAD+ in Brain Aging and Neurodegenerative Disorders

Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson’s disease
Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson’s disease

Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1)
Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1)

Differential Sirtuin Expression Patterns in Amyotrophic Lateral Sclerosis (ALS) Postmortem Tissue: Neuroprotective or Neurotoxic Properties of Sirtuins in ALS?
Differential Sirtuin Expression Patterns in Amyotrophic Lateral Sclerosis (ALS) Postmortem Tissue: Neuroprotective or Neurotoxic Properties of Sirtuins in ALS?

CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells
CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells

CD38 is critical for social behaviour by regulating oxytocin secretion
CD38 is critical for social behaviour by regulating oxytocin secretion

CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval
CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval

CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves
CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves

Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation
Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer’s disease
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer’s disease
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